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I've always had an issue with this one. "Key takeaway: if you want to make sure your results are reliable, rerun your experiments".. Yes, replication is gold standard. But you're inflating false positive rate in a single replication. So, let's say you had a test result that came back with a negative signal and you really believed in the feature because of research or whatever, so you re-test assuming it was a false positive. This time, result is neutral, but, of course, no stat sig. Which result? So you treat again... Now, time and samples are confounding and we're not even really replicating. It may be minor, or it could be a huge impact to reaction to your treatment. 🤷‍♀️

Swag Valance's avatar

Fantastic summary. Thanks!

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